CLENBUTEROL (Clenbuterol Hydrochloride)

Clenbuterol belongs to a class of drugs known as sympathomimetics. These drugs affect the sympathetic nervous system in numerous ways. It is specifically a selective beta-2 sympathomimetic, stimulating the beta-2 receptors, which creates a thermogenic effect, directly stimulating fat cells and accelerating the breakdown of triglycerides to form free fatty acids. Animal studies have also shown it to be quite anti-catabolic and/or anabolic which obviously leads to its attractiveness amongst bodybuilders – particularly during the pre-contest phase. However, it has to be said that these studies have been restricted to animals and there is little real evidence of Clenbuterol having muscle building/sparingproperties in humans. This does little to tarnish its reputation as a great adjunct anabolic – used both off-season and pre-contest.

ACTIVE LIFE

Another attractive quality of this drug is its extremely long half-life in the body – which gives it an active life of approximately 34-36 hours. This makes it easy to maintain steady blood levels with a single or twice daily dosing schedule. Interestingly enough, Clenbuterol has never been approved for use in the USA (perhaps the drug companies would not find it profitable enough). This does little to affect its availability on the black market however, with many foreign preparations being readily available.

is generally a drug where you have to gradually assess your own individual tolerance level. Basically, it is advisable to start with 20mcgs upon rising. If the side effects (possible anxiety, shaking and sweating) are not too pronounced, then the same dose can be repeated later in the day. Men generally end up in the range of 2-8 tablets a day. Women usually find 2-4 to be very effective.

As previously suggested, Clenbuterol does have a fair amount of side effects – most of which will be familiar to anyone who has used CNS stimulants. Along with a slight increase in body temperature (due to the thermogenic effect) users may experience shaky hands, insomnia, sweating, increased blood pressure and nausea. These side effects usually become less noticeable once the user becomes accustomed to the drug. They are also dose dependant – which is why it is always advised to begin on a low dose in order to gauge your tolerance level.

DRAWBACKS ASSOCIATED WITH CLENBUTEROL USE

One of the main drawbacks with this drug is that after a couple of weeks it seems to stop working for most people. This is due to the fact that it can cause a down regulation of the beta-receptors in the pulmonary, cardiac and Central Nervous System. One way to sense this down regulation is when you no longer feel an elevation in body temperature following administration. This suggests that the substance is no longer exhibiting a thermogenic effect. At this point increasing the dosage would not be very effective and a break of at least two weeks should be taken before it is used again. This accounts for the popular two weeks on/two weeks off method of administration. There is however much controversy in this area. Some say it can promote fat loss for approximately 4-6 weeks, though any strength gains can usually only be felt for 3-4 weeks (probably due more to the stimulant properties rather than any real anabolic effect).

The use of anti-histamines such as Benadryl or Ketotifen every 3^{rd or 4th week may help prevent this tolerance to some extent – although they should be taken at bedtime since they will cause drowsiness.}

^{It has also been found that Clenbuterol depletes the body of the amino acid Taurine, so you may want to supplement with this during a cycle of Clenbuterol.}

^{SAFETY PRECAUTIONS}

^{However you decide to incorporate this substance into your program, you must always start low and never go above 8 tablets a day (with a complete maximum being 200mcgs). Monitor your blood pressure and keep it at (or below) 140/90. If it goes above that, or if side effects become intolerable use your common sense and decrease the dose.}

^{ENHANCING THE EFFECTS}

^{Many competitive athletes find that the fat burning effects of Clenbuterol can be enhanced by combining it with thyroid hormones (particularly Cytomel). The thermogenic effect in this instance can be very powerful. When combined these cutting agents can even counter the fat storing effects of strong aromatizing androgens. A Clenbuterol / thyroid mix is also common when using human growth hormone, as it seems to increase the thermogenic and anabolic effect significantly.}

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Clenbuterol (Balkan Pharmaceuticals) tab;

 Clenbuterol is a very interesting and remarkable compound. It is not a steroid hormone but a beta-2-symphatomimetic. Clenbuterol, above all, has a strong anti-catabolic effect, which means it decreases the rate at which protein is reduced in the muscle cell, consequently causing an enlargement of muscle cells. For this reason, numerous athletes use Clenbuterol after steroid treatment to balance the resulting catabolic phase and thus obtain maximum strength and muscle mass. A further aspect of Clenbuterol is its distinct fat-burning effect. Clenbuterol burns fat without dieting because it increases the body temperature slightly, forcing the body to burn fat for this process. Due to the higher body temperature Clenbuterol magnifies the effect of anabolic/androgenic steroids taken simultaneously, since the protein processing is increased.